Abstract for the Symposium on Innovative Polymers for Controlled Delivery

نویسندگان

  • Sébastien Cajot
  • Christine Jérôme
چکیده

for the Symposium on Innovative Polymers for Controlled Delivery 1 TAILOR-MADE COPOLYMERS FOR RESPONSIVE DRUG DELIVERY NANOSYSTEMS Sébastien Cajot, Christine Jérôme Center for Education and Research on Macromolecules (CERM), University of Liege, B6 Sart tilman, B-4000 Liege, Belgium. e-mail: [email protected] Summary Amphiphilic macromolecules combining a biodegradable and a bioeliminable block have been synthesized in order to build micellar drug delivery systems. Particularly, redox reversible disulfide linkages have been introduced in the structure to ensure cross-linking of the micelles formed in water and prevent their dissociation at high dilution upon injection. The synthesis of polymers and their micellization will be especially emphasized in this paper.

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تاریخ انتشار 2010